Last edited by Mazukinos
Tuesday, May 5, 2020 | History

2 edition of Synthetic polypeptides as antigens found in the catalog.

Synthetic polypeptides as antigens

Synthetic polypeptides as antigens

  • 67 Want to read
  • 33 Currently reading

Published by Elsevier in Amsterdam .
Written in English

    Subjects:
  • Peptides -- Immunology.,
  • Peptides -- Synthesis.

  • Edition Notes

    StatementM.H.V. Van Regenmortel ... [et al.].
    SeriesLaboratory techniques in biochemistry and molecular biology -- v. 19
    ContributionsVan Regenmortel, M. H. V.
    Classifications
    LC ClassificationsQH324 .L32 v.19
    The Physical Object
    Paginationxv, 227 p. :
    Number of Pages227
    ID Numbers
    Open LibraryOL20341531M
    ISBN 100444809759

    Abstract. In the lung alveolar macrophages (AM) are the first cells to encounter pathogens and airborne antigens. In general, AM function poorly as accessory cells and even inhibit T cell proliferation in vitro 1, previous experiments it was found that the increased numbers of dendritic cells (DC) in the bronchoalveolar lavages after intratracheal instillation of Bacillus Cited by: 4. GOULD HJ, GILL TJ, 3rd, KUNZ HW. STUDIES ON SYNTHETIC POLYPEPTIDE ANTIGENS. XII. THE EFFECTS OF PH, IONIC STRENGTH, TEMPERATURE, AND NONAQUEOUS SOLVENTS ON ANTIBODY ACTIVITY AND THE ANTIBODY-SYNTHETIC POLYPEPTIDE INTERACTION. J Biol Chem. Sep; – MAURER PH. Antigenicity of polypeptides Cited by: 6.

      Synthetic peptide vaccines Most existing vaccines are prepared from an attenuated version of the pathogen or from inactivated disease-causing organisms or a suitable part of it e.g. a toxin. However, often the antigen to which the immune system responds is a relatively small number of amino acids or peptide. Polypeptides are fascinating materials with unique properties for various biological materials. We highlight here recent advances in amino acid N-carboxyanhydrides (NCAs) and synthetic polypeptides from the aspects of chemistry, self-assembly and biological synthetic methodologies, mechanistic studies and optimization of polymerization conditions Cited by:

      Characteristics of Antigens• Chemical nature of antigens: – proteins – polysaccharides – lipopolysaccharides – nucleoproteins – glycoproteins – steroid hormones – bacterial cells, viruses – synthetic polypeptides – synthetic polymers1/5/ MD 4 5. Design of peptide and polypeptide vaccines Tamar Ben-Yedidia and Ruth Arnon* Advances have been made in the development of vaccines based on synthetic peptides and polypeptides representing tumor-associated antigens and protective epitopes of viruses and parasites. Advances within the past year include the.


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Synthetic polypeptides as antigens Download PDF EPUB FB2

Synthetic Polypeptides As Antigens (Laboratory Techniques in Biochemistry & Molecular Biology) (v. 19) by M. Van Regenmortel (Author), J. Briand (Author), S. Muller (Author), S. Plaue (Author) & 1 more ISBN Cited by:   Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their immunochemical activity by a variety of immunoassays.

This book also describes methods for analyzing the antigenic structure of proteins and predicting the location of their antigenic Book Edition: 1. Synthetic Polypeptides as Antigens Edited by R.H. Burdon, P.H. van Knippenberg Vol Pages ii-xv, (). Synthetic polypeptides as antigens. [M H V Van Regenmortel;] Book, Internet Resource: All Authors / Contributors: M H V Van Regenmortel.

Find more information about: ISBN: # Antigens: Synthetic peptides\/span>\n \u00A0\u00A0\u00A0\n schema. COVID Resources.

Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has Synthetic polypeptides as antigens book together information and resources to assist library staff as they consider how to handle.

The book also describes antigenicity of proteins and methods to localize antigenic sites as well as methods for predicting epitoxes, and gives detailed protocols for peptide-carrier.

Synthetic peptides as antigens Ciba Foundation Symposium Chairman: Gordon L. Ada Vaccination is a major means of combating infectious disease but no effective vaccine is available yet for many parasitic, viral and bacterial infections.

A new approach consists of vaccines based on synthetic peptides rather than native parent antigens. Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology.

Those using synthetic peptides as immunological probes will find this a most useful book, as will those wishing to overcome the difficulties of achieving antigenic mimicry by synthesis. Synthetic Polypeptides-The polypeptides were synthesized by polymerization of the N-carboxyanhydrides in a 1 y.

solution in benzene or in 95 y. benzene and 5 y. nitrobenzene with the use of sodium. In this comprehensive book, the authors discuss peptide synthesis and application within the context of their increasing importance to the pharmaceutical industry.

Peptides: Synthesis, Structures, and Applications explores the broad growth of information in modern peptide synthetic methods and the structure-activity relationships of synthetic. Studies on Synthetic Polypeptide Antigens XIX. IMMUNOGENICITY AND ANTIGENIC SITE STRUCTURE OF INTRAMOLECULARLY CROSS- LINKED POLYPEPTIDES* (Received for publication, Ap ) THOMAS J.

GILL. Synthetic polypeptides, the analogues of natural proteins, are important biomaterials that have found broad biomedical applications. Ring-opening polymerization of N-carboxyanhydrides offers a reliable way to prepare high-molecular-weight polypeptides in large scale with diverse side-chain functionalities.

The past two decades have seen significant Cited by: 3. Synthetic Polypeptides as Antigens is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology, and microbiology.

Those using synthetic peptides 5/5(2). Abstract. Synthetic polypeptides from the ring-opening polymerization of N -carboxyanhydrides (NCAs) are one of the most important biomaterials. The unique features of these synthetic polypeptides, including their chemical diversity of side chains and their ability to form secondary structures, enable their broad applications in the field Cited by: SYNTHETIC POLYPEPTIDES.

by C.H. Bamford et al. and a great selection of related books, art and collectibles available now at The nomenclature of the synthetic polypeptides is modified from that defined in the Tentative Rules on Abbreviated Nomenclature of Synthetic Polypeptides [Europ.

Biochem. 3, – ()]. The other abbreviations are defined in their context. Ab Cited by: 8. Synthetic polypeptides have the advantage of being composed of much simpler components than natural proteins, but do not present the complex biological activity of a protein.

However, due to their 3D structure and biocompatibility, polypeptides have become the most promising materials in many bio-applications, such as drug and gene delivery. Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing the.

Synthetic Polypeptides as Antigens: Laboratory Techniques in Biochemistry and Molecular Biology, Vol19 (Volume 19) M.H.V. Van Regenmortel Published by Elsevier Science Ltd (). Much effort has been put into the study of synthetic antigens. The literature is so extensive that no attempt is made to cover it, even in a superficial way.

Maurer (), Sela (), and Schlossman () have written articles to which readers are referred. A very large number of synthetic polypeptides has been described. T LYMPHOCYTES express either αβ or γδ T-cell receptor heterodimers1,2. Most αβ T cells recognize antigenic peptides bound to major histocompatibility complex molecules but the antigen Cited by: Synthetic polypeptides from the ring-opening polymn.

of N-carboxyanhydrides (NCAs) are one of the most important biomaterials. The unique features of these synthetic polypeptides, including their chem. diversity of side chains and their ability to form secondary structures, enable their broad applications in the field of gene delivery, drug Cited by: 6.A synthetic vaccine is a vaccine consisting mainly of synthetic peptides, carbohydrates, or antigens.

They are usually considered to be safer than vaccines from bacterial cultures. Creating vaccines synthetically has the ability to increase the speed of production. This is especially important in the event of a pandemic.